Cancer is projected to soon overtake heart disease as the leading cause of death in California. It already is in San Diego and 22 states. This year alone, more than 176,000 residents will be diagnosed with cancer, and nearly 60,000 will die from it. The estimated cost burden of cancer in California is $14 billion. To better fight this scourge, the University of California’s five academic cancer centers have formed a new consortium to share new approaches and treatments, data, minds, resources and more. The five centers comprising the Consortium are UC San Diego Moores Cancer Center, UC Davis Comprehensive Cancer Center, UC Irvine Chao Family Comprehensive Cancer Center, UCLA Jonsson Comprehensive Cancer Center and UC San Francisco Helen Diller Family Comprehensive Cancer Center. “The Consortium is unprecedented in size and ambition,” said Scott Lippman, director of Moores Cancer Center. “Some of the world’s best cancer physicians and scientists will now be able to collaborate in ways impossible before, benefitting tens of thousands of patients throughout the state.” UC physicians and scientists will advance work in precision medicine, clinical trials, population health science, big data best practices and political engagement for public interest. Each center brings particular interests, resources, and strengths. Experts are available at Moores Cancer Center to discuss what the consortium means in terms of cancer research and treatment, present and future.